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  • SP600125: Precision JNK Inhibition for Next-Gen Neuroinfl...

    2025-10-21

    Explore SP600125, a selective ATP-competitive JNK inhibitor, and its advanced applications in neuroinflammation and neuronal differentiation. This deep-dive offers unique mechanistic insights and translational strategies, surpassing conventional perspectives on JNK pathway modulation.

  • Filipin III: Unveiling Cholesterol’s Role in Immunometabo...

    2025-10-20

    Explore the advanced scientific landscape of Filipin III, a cholesterol-binding fluorescent antibiotic, in immunometabolic research and tumor microenvironment analysis. This in-depth article reveals novel applications and mechanistic insights, distinguishing it from standard membrane cholesterol visualization guides.

  • (-)-Arctigenin: Next-Generation Modulator of Tumor Microe...

    2025-10-19

    Discover how (-)-Arctigenin, a potent Arctigenin natural product, uniquely targets NF-κB and MAPK/ERK pathways to modulate tumor microenvironment signaling and inhibit HIV-1 replication. This article delivers advanced insights into its mechanistic action, differentiation from current research, and translational potential.

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